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Thus, statins become indispensable in the management of all ranges of CVDs from stable angina through acute MI and on to HF ( Table 1 )

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4.4 HIF-1/2 inhibitors as a therapeutic target Despite standard protocol consisting of surgical resection, radiotherapy, and chemotherapy that have remained largely unaltered since 2005, GBMs aggressive nature to recur continues to challenge the medical community for more novel therapeutic approaches (156)