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This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients
There are two types of ATTR-CM: hereditary (familial) ATTR-CM, also called hATTR-CM, and wild-type ATTR-CM
At lower doses like 1-2mg, the GLP-1 effect is mild
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