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The SURPASS-4 clinical trials concluded that In people with type 2 diabetes and elevated cardiovascular risk, tirzepatide, compared with glargine, demonstrated greater and clinically meaningful HbA1c reduction with a lower incidence of hypoglycemia at week 52. What is Mounjaro (tirzepatide)

The secondary outcomes comprising cardiometabolic risk factors (including high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), body mass index (BMI), insulin sensitivity index adjusted for BMI (ISI), systolic blood pressure (SBP), diastolic blood pressure (DBP)) [33] and multiple-organ complications (liver diseases: metabolic dysfunction-associated steatohepatitis, liver fibrosis, fibrosis in MASLD, liver cirrhosis, hepatocellular carcinoma (HCC), hepatic failure

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This is actually a positive sign, since platforms that approve everyone regardless of medical history are cutting corners on safety