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First, women have a lower total body water percentage (~49% vs ~58% in men), so alcohol concentrates into a smaller volume and produces a higher blood alcohol level
Moreover, low levels of B12 reduce the supply of oxygen, which leads to a decrease in the RBC count
Copper-catalyzed oxidation of methionine and histidine side chains is well-documented chemistry, and so is copper-mediated cleavage of a peptide backbone at coordination sites
The information in this guide applies specifically to lyophilized (freeze-dried powder) vials that require reconstitution
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