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Adverse Reactions/Side Effects The following important adverse reactions are described below and elsewhere in the labeling: Lactic Acidosis [see Boxed Warning and Warnings and Precautions (5.1)] Diabetic Ketoacidosis in Patients with Type 1 Diabetes Mellitus and Other Ketoacidosis [see Warnings and Precautions (5.2)] Volume Depletion [see Warnings and Precautions (5.3)] Genitourinary Infections, including Urosepsis, Pyelonephritis, Necrotizing Fasciitis of the Perineum (Fournier's Gangrene), and Genital Mycotic Infections [see Warnings and Precautions (5.4)] Hypoglycemia [see Warnings and Precautions (5.5)] Lower Limb Amputation [see Warnings and Precautions (5.6)] Hypersensitivity Reactions [see Warnings and Precautions (5.7)] Vitamin B12 Deficiency [see Warnings and Precautions (5.8)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice
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"It is important to remember that alcohol isn't a benign substancedrinking too much is associated with a higher risk of most cancers, heart disease, high blood pressure and depression." Frequently Asked Questions How much water should you drink while drinking alcohol
All serums may not deliver the same before-and-after outcome
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