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La extrapolacin de estas dosis al ser humano, utilizando los factores de conversin alomtricos estndar (factor de 6,2 para la rata), da dosis tericas del orden de 1,6 g/kg en humanos
The second approved indication is for chronic weight management in adults with obesity (BMI 30 kg/m) or those who are overweight (BMI 27 kg/m) with at least one weight-related comorbidity, such as hypertension, dyslipidaemia, or obstructive sleep apnoea
Handb Exp Pharmacol 233: 437459, 2016
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