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Problems in GLP-1RA development Cost-effective and reliable trial endpoints for MASLD medication Assessing long-term liver benefits in clinical trials has remained a complex issue

to reduce the risk of major adverse cardiovascular (CV) events (CV death, non-fatal myocardial infarction or non-fatal stroke) in adults with type 2 diabetes mellitus who are at high risk for these events

Thus, the cerebro-protective effects of DPP-4 inhibition may be another consideration for treatment of T2DM patients at risk for development of cerebrovascular disease or cognopathy

Your doctor can help you decide if taking both medications is the best option for you, based on your health needs and how your body responds to each drug