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In contrast, the wide dynamic range of RT allows for monitoring of the GSH level changes within 110 mM in both directions in living cells (Fig

Furthermore, it was found that the general control of amino acid synthesis 5-like 1 (GCN5L1) negatively regulates both mitochondrial biogenesis and degradation pathways through acting on both PGC1a and TFEB in mouse embryonic fibroblasts (Scott et al., 2014)

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