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doi: 10.1016/S1472-6483(10)60008-9 21 ShaikhNMukherjeeAShahNMeherjiPMukherjeeS
Research Support and Efficacy Numerous clinical trials have demonstrated the effectiveness of semaglutide for weight loss: Clinical Trials : In a pivotal study involving approximately 2,000 adults with obesity or overweight (without diabetes), those using semaglutide in conjunction with lifestyle modifications lost an average of 14.9% of their body weight over 68 weeks, compared to a mere 2.4% weight loss in the placebo group
The first 48 hours after injection are typically when side effects are strongest
This cardiovascular effect has been observed across studies involving GLP-1 receptor agonist medications
