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Two potent therapeutic strategies based on the GLP-1 system have been developed for the treatment of type 2 diabetes [1]
10.1016/j.ypmed.2013.09.023
The activation of PP5 family phosphatase is usually triggered by arachidonic acid, which induces a conformational change of the TPR domain, thereby disrupting the TPRPPase interaction 25,39
Our observation that condensed cells no longer accumulate biomass at the time of condensation suggests, consistent with recent work from the Zhao and Drlica groups 11 , that antibiotic-treated cells can die substantially after antibiotic treatment, and that this cell death is not revealed by traditional time-kill experiments in which cells are assumed to have died at the time of plating
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