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GLP-1 RAs not only ameliorate insulin resistance and microvascular injury [84], which are significant determinants of depression in T2DM, but also enhance dopamine metabolism and stimulate growth factor signaling pathways, suggesting potential neuroprotective functions [85,86]
Then tirzepatide added a second mechanism and raised the ceiling
When used in medical weight loss programs, such as in Southlake, these peptide injections mimic gut hormones post-meal, signaling fullness and diminishing hunger
Under experimentally induced oxidative stress conditions using hydrogen peroxide, BPC 157 appeared to support fibroblast survival relative to untreated controls
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