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Contraindications Active cancer: BPC-157 promotes new blood vessel formation and cell migration, the basis for the caution flagged in active malignancy Pregnancy/breastfeeding: insufficient safety data Within 2 weeks of surgery: excessive angiogenesis may complicate wound closure Bleeding disorders or therapeutic anticoagulation: the animal clotting-time findings point in opposite directions by species and there is no human coagulation data, so the registered trial excludes both groups Monitoring No specific monitoring protocol has been established