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SmilowitzNRKunichoffDGarshickMShahBPillingerMHochmanJSet alC-reactive protein and clinical outcomes in patients with COVID-19

One example entering trials is ex vivo cytokine-treated monocytes essentially training a patients monocytes to be more anti-inflammatory and better at phagocytosis by culturing them with IL-4/IL-10, then infusing them back (this approach is being tested in sepsis under the name GM-CSF tuned monocytes)

Huang P, Chen Y, Lin H, Yu L, Zhang L, Wang L, Zhu Y, Shi J (2017) Molecularly organic/inorganic hybrid hollow mesoporous organosilica nanocapsules with tumor-specific biodegradability and enhanced chemotherapeutic functionality

In addition, the oxidants may also originate from cytosolic enzyme systems, e.g., NADPH oxidases, and from exogenous triggers such as ionizing radiation and chemotherapeutics