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Improve neurological deficit score (NSS)
10.1002/biof.1111 193 WandersD.ForneyL
Some fructose-derived RCS have been identified in vivo (Figure 2), for example, glycolaldehyde and acrolein
According to the previous conclusions, the factors such as semen volume, total sperm count, sperm motility, and normal morphology of sperm decrease and percentage of DNA fragmentation increases following male aging.5,6 Declined number of Leydig cells and its subsequent reverse impact on gonadotropins secretion is reported previously.21 Increased thickness of basement membrane of seminiferous tubules, reduced seminiferous epithelium as well vascularization of testicular tissue are other important testicular problems in aged males.22 In addition, the frequency of chromosomal aneuploidies was increased in sperm from aged men.9 Elevated ROS production in the testicles of aged male leads to raised lipid peroxidation, DNA damages, apoptosis, and several cellular complications.5 A number of documents have exposed detrimental effects of increased testicular ROS production on sperm quality.2325 Imbalance between pro and anti-inflammatory elements can be considered as one of the possible mechanisms involved in injuries caused by aging in reproductive organs, especially the testicles
