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The intermediates from de novo lipogenesis in the liver will disrupt mitochondrial function and produce ROS, and then cause endoplasmic reticulum (ER) stress, ultimately leading to inflammation, and the broken cells releasing cytokines will cause more cell death (Huang et al., 2025)
Compared with the control group, study participants who supplemented with taurine had a significant improvement in the primary outcome of reducing risk of metabolic syndrome, demonstrated by the following weighted mean changes: systolic blood pressure - 4 mm Hg diastolic blood pressure -1.5 mm Hg triglycerides -18.3 mg/dL fasting blood glucose -5.9 mg/dL There were also significant improvements in secondary outcomes as shown by the following weighted mean changes: LDL cholesterol - 6.5 mg/dL total cholesterol - 8.3 mg/dL fasting insulin -1.52 IU/L HOMA-IR (calculation of insulin resistance) - 0.7 There was no significant effect on HDL, body weight, and BMI
Anecdotally, weve heard of some people coming back, men specifically, saying that GLP-1s have helped their libido and sexual performance, Tchang said
Expert Opin Drug Metab Toxicol 6:153170
