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Conversely, exposing to H 2 O 2 alone did not significantly alter the expression of Nrf2 and HO-1 compared to the control group (Fig

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The unbalanced interaction between oxidants and antioxidants has an impact on reproductive pathologies such as abnormalities in oocyte metabolism endometrial maturation through the activation of nuclear factor-kappa B (NF-) and nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant signaling pathways, endometriosis, polycystic ovarian syndrome (PCOS), infertility, prenatal development disorders, and complications