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doi: 10.1016/j.ijom.2018.08.006 17 Gaiger de OliveiraMThompsonLDChavesACRadosPVda Silva LauxenIFilhoMS
Under basal conditions, NRF2 is kept inactive through binding to its negative regulator KEAP1, which is a redox-regulated substrate adaptor for the Cullin (Cul)3-RING-box protein (Rbx)1 ubiquitin ligase complex that directs NRF2 for degradation [10]
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Rare risks , especially if the infusion is not administered correctly, include hypotension (low blood pressure) from a rapid magnesium infusion, arrhythmias, or vein irritation
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