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Minocycline attenuates pain by inhibiting spinal microglia activation in diabetic rats
As obesity rates remain high in the U.S., millions of people are exploring medical weight management options
For these individuals, as well as those living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and dysautonomia, exhaustion is not just feeling tiredit is a profound, cellular depletion of energy
A key concept for understanding this interface is the model of allostasis (adaptation) and allostatic load (pathophysiology) [6] that we review below examining this model in relation to new insights from the recent work on the link between mitochondrial metabolism and epigenetic function to promote healthy behaviors and cognitive function
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