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(Source: iPharma Pharmacy, 2026) A 2026 systematic review and meta-analysis (Prospero CRD42024535096) searched Cochrane Library, EMBASE, and Medline through September 2024, identifying 9,654 studies and including 11 randomized controlled trials comparing GLP-1 receptor agonists against no treatment, placebo, lifestyle intervention, oral contraceptives, anti-androgens, or metformin in PCOS patients
Injection site reactions including temporary redness, swelling, or discomfort occur occasionally
The comparison with retatrutide is numerically striking but requires careful framing
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