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The article names a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, uncontrolled severe diabetes, severe renal impairment, and concurrent use of other weight-loss medications as contraindications

[1] Patients should be informed about the risk of gallbladder disease and advised to report symptoms suggestive of gallstones

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Patient-information materials should emphasize that Bi-Amino Injection is a compounded preparation that has not been reviewed by the Food and Drug Administration for safety or efficacy, and that ongoing laboratory assessment-electrolytes, acid-base status, and renal function-forms an integral part of therapy