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Treatment goals and tolerability are reviewed together.
[7] In STEP-4 (N=803), participants who continued semaglutide after a 20-week run-in maintained or further reduced their weight, while those who switched to placebo regained 6.9 percentage points of body weight by week 68
Over time, consistent use combined with lifestyle changes can lead to what some call metabolic flexibilitythe bodys ability to efficiently switch between burning carbs and burning fat for fuel
Standard-dose GLP-1 research suggests these medications may support reductions in weight when paired with changes in diet and activity
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