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Off-label prescribing accounts for roughly 20% of all prescriptions written in the United States
But the sticker prices of these injectable drugs remain expensive about $700 to $1,350 for a months supply at the highest and the costs have fallen on patients and their insurance providers
The SURMOUNT clinical trials investigating tirzepatide for weight management have reported headaches in participants, but this remains investigational for this indication in the UK
Sources Novo Nordisk Wegovy HD (semaglutide 7.2 mg) FDA approval announcement, March 2026 The Lancet Diabetes & Endocrinology STEP UP trial: once-weekly semaglutide 7.2 mg in adults with obesity (2025) FDA Wegovy (semaglutide) prescribing information, 2025 PR Newswire FDA approves Wegovy HD injection (Novo Nordisk press release) NovoCare Wegovy cost and coverage information ClinicalTrials.gov STEP UP trial protocol (NCT05646706) New England Journal of Medicine STEP 1 trial: once-weekly semaglutide 2.4 mg Medical disclaimer This article is for informational purposes only and does not replace medical advice
