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(More information) Deficient/low status of riboflavin interferes with the metabolism of folate, particularly in individuals with the variant 677TT genotype in MTHFR
The 5-oxoprolinase may regenerate glutamate from 5-oxoproline, but in an ATP-depleting futile cycle that eventually results in a progressive depletion of ATP and further accumulation of 5-oxoproline (Fig
Nutr Cancer 1993
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