Liver disease fatty liver, alcohol-related liver disease, and chronic hepatitis all elevate ferritin Frequent blood transfusions transfusional iron overload Excessive iron supplementation taking iron without confirmed deficiency Why it matters: Untreated iron overload deposits iron in the liver, heart, pancreas, and joints leading to cirrhosis, cardiomyopathy, diabetes, and arthritis
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Additionally, it counteracts rat hind limb ischemia by accelerating blood flow recovery and vessel number (Hsieh et al., 2017)
Importantly, if you have unexpectedly high B12 levels without taking supplements or receiving injections, this warrants GP review as it may indicate underlying liver disease, kidney disease, or certain blood disorders