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Therefore, during DUL treatment, we should pay close attention to the related signs of pancreatitis, and if pancreatitis occurs, we need to stop the drug immediately (113)

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Liraglutide reduced astrocytes, microglia activity and amount of A levels in cortical and hippocampal CA1 and CA3 regions in 5FAD mice (147)

The manufacturer recommends that patients using oral hormonal contraceptives switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after tirzepatide initiation and for 4 weeks after each dose escalation