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doi: 10.1056/NEJMcp1710945 89 SinghNBabyDRajguruJPPatilPBThakkannavarSSPujariVB
Because of that, the NICE recommendations lean towards individualised care: tailoring the dose, frequency and delivery method, following people up at around three months, and reviewing sooner if symptoms are severe or if someone is pregnant or breastfeeding
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These drugs exhibit anti-inflammatory and immunoregulatory properties while promoting cell autophagy and phagosome maturation by inhibiting the mammalian target of the rapamycin (mTOR) signaling pathway [8]
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