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References Pickart L, Thayer L, Thaler MM

"Glutathione and immune function." Proc Nutr Soc

Arthritis Rheumatism (2010) 62(9):271625

Common cardiovascular MTHFR symptoms include: Elevated homocysteine levels often discovered through blood tests High blood pressure persistent hypertension without clear cause Heart palpitations irregular heartbeat, racing heart, or fluttering sensations Blood clots increased risk of deep vein thrombosis (DVT) or pulmonary embolism Stroke or heart attack risk particularly in younger individuals with family history Poor circulation cold hands and feet, numbness, or tingling Why this happens: When methylfolate is attached to homocysteine, it is converted into methionine (a beneficial amino acid)