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Compared to untreated MAFLD counterparts, several lipid metabolism-related signaling pathways and functional networks were aberrantly enriched, including PPAR signaling pathway, Vascular smooth muscle contraction, Regulation of lipolysis in adipocytes, Aldosterone synthesis and secretion, Fat digestion and absorption, and Vitamin digestion and absorption. Notably, Regulation of lipolysis in adipocytes, Fat digestion and absorption, and Vitamin digestion and absorption are closely linked to the processes of lipid metabolism and deposition, while Vascular smooth muscle contraction and Aldosterone synthesis and secretion may be related to the development of hepatic fibrosis

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