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A Coordinated Defense for Neuronal Energy Both estrogen and GLP-1 receptors are expressed in the brain regions most critical to cognition, including the hippocampus, the structure central to memory formation, and the prefrontal cortex, which governs executive function and decision-making [2]

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Noom, Calibrate, and Embla say there is preliminary data to support their contention that many people can maintain weight loss through exercise and diet after stopping the medications (though some of the doctors Fortune spoke with were skeptical of those studies)

They are medically-proven to treat obesity and lower the risk of chronic diseases