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The HealthRX.com clinical team uses a structured 4-step appeal framework for Anthem Eliquis denials: (1) obtain the written denial with specific criteria language, (2) have the prescriber request an urgent peer-to-peer within 24 hours, (3) attach ARISTOTLE trial data and the ACC/AHA guideline Class I recommendation to the written appeal, and (4) simultaneously enroll the patient in the BMS/Pfizer bridge supply program to prevent therapy interruption during the appeal period