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For RNAscope/IHC validation, mice were fed 0.3% CPZ pellets (Envigo TD.140805) for 5 consecutive weeks, and then either sacrificed as described below at the end of 5 weeks for the demyelination timepoints, or returned to normal chow and collected 3 or 5 weeks later for the remyelination and late recovery timepoints

They may be different in color, size, shape, and non-active fillers

The assessment part will include a detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration, and ongoing product development activities related to GLP-1 agonists

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