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These structural interfaces are defined as regions in which organelle membranes are brought into proximity, typically within 1080 nm, thereby enabling direct communication and non-vesicular exchange of ions, lipids, and signaling molecules without membrane fusion (Cali et al., 2025)

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The high cost of branded GLP-1 medications, which range from $936 to $1,349 per month before insurance and about $1,000 for uninsured patients, presents a significant financial barrier for many individuals

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2c,d) and a trend toward more triglyceride (TG) accumulation (Fig

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However, analysts polled by FactSet projected even higher quarterly sales for the GLP-1 drugs, forecasting $3.77 billion for Mounjaro and $1.73 billion for Zepbound

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