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One of the most commonly used experimental models of IBD is the administration of an enema containing the contact-sensitizing allergen trinitrobenzenesulfonic acid (TNBS) in ethanol resulting in the development of macroscopic, histologic, and biochemical alterations that are well-characterized (Rachmilewitz et al, 1989
doi: 10.3389/fimmu.2026.1758379 Received 01 December 2025 Revised 05 March 2026 Accepted 05 March 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Varun Sasidharan Nair, Italian Institute of Technology (IIT), Italy Reviewed by Mahmoud Abdelrahman Alkabbani, Egyptian Russian University, Egypt Lingjie Meng, Zunyi Medical University, China Updates Copyright 2026 Sivalingam
R.Izpisa BelmonteJ
Regioselective glutathione conjugation of the carcinogen, 7, 12-dihydroxymethylbenz[a]anthracene, via reactive 7-hydroxymethyl sulfate ester in rat liver cytosol
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