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However, another study confirmed that the mean TMAO levels did not change during the lifestyle intervention (Randrianarisoa et al., 2016)

Smaller doses may help reduce this effect

Your healthcare provider may recommend baseline kidney function tests and repeat testing at 3 months and 6 months after starting tirzepatide, since many DOACs depend on renal clearance and weight loss can improve kidney function

| Last Updated: January 30th, 2024 Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist (RA) that is manufactured by Eli Lilly and Company