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IM injections are the standard for rapidly restoring B12 levels, particularly in severe cases and patients with absorption issues
From a scientific standpoint, MC4R deficiency presents a formidable challenge for treatment with MC4R agonists like setmelanotide due to extreme genetic and functional heterogeneity
Some patients eventually transition off medication
One of these applications describes pairing GLP-1 medications with another type of drug that blocks orexin receptors (orexin-1 or orexin-2) in the brain for treating opioid addiction
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