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Chauhan et al., 2012)
Given the potential effects on angiogenesis and tissue growth, patients should be monitored for any signs of abnormal tissue proliferation or changes that could indicate malignant transformation
NAC may help by supporting antioxidant defenses and reducing oxidative stress, though its effects vary depending on the population and fertility issue being studied.32 In men, one randomized trial found that 600mg of NAC, selenium, or the combination improved semen parameters, with the combination producing stronger effects than either ingredient alone.23 In women undergoing assisted reproduction, NAC has also been studied for oocyte and embryo quality, though this research is still relatively early and not definitive.24 PCOS NAC has attracted particular interest in PCOS, where insulin resistance, inflammation, and oxidative stress often overlap.17 Researchers think NAC may help by improving insulin sensitivity and reducing oxidative stress, which may, in turn, support ovulation and reproductive function
It was added to the Prohibited List in 2022 as a non-approved substance, reflecting its transition from an obscure research compound to a significant "substance of interest" in professional athletics
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