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doi: 10.1001/jama.2009.2025, 47 GearhardtA
The safety, tolerability, pharmacokinetics and cognitive effects of GSK239512, a selective histamine H3 receptor antagonist in patients with mild to moderate Alzheimers disease: a preliminary investigation
Sample name: the product of the invention (batch number P-110201, specification 0.6g) Preparing a compatible injection: 0.9% sodium chloride injection, manufactured by Chongqing Di kang Yangtze pharmaceutical Co., Ltd 5% glucose injection, manufactured by Tai Ji southwest pharmaceutical industries, Ltd 10% glucose injection, manufactured by Tai Ji southwest pharmaceutical industries, Ltd Water for injection, made by Investigation time: 0h, 2h, 4h and 6h And (4) investigation indexes are as follows: the results of the product of the invention in four injections at ambient temperature conditions (dilution to measured concentration, measured only at 0h, 2h, 4h, 6 h) for clarity, pH, visible foreign matter, insoluble particles, related substances (area normalization) are shown in tables 7-8
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