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This ingredient has been widely used to address several skin problems, including acne, psoriasis, rough and bumpy skin (also known as keratosis pilaris), photodamage, and melasma 8

pubmed.ncbi.nlm.nih.gov/16352683 Raun K, et al

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Most commonly reported: Nausea (most common, particularly during dose escalation) Diarrhea Vomiting Constipation Abdominal discomfort These effects were generally mild to moderate in severity and tended to diminish as participants adjusted to the treatment, particularly when gradual dose escalation protocols were followed