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The brain is highly susceptible to oxidative stress, which increases during ageing and is considered a major contributor to neurodegeneration
Certain genetic variants in glutathione synthesis enzymes (GCLC, GCLM, GSS) and metabolism pathways influence how efficiently your body produces and recycles glutathione
A separate Phase 2 trial in type 2 diabetes evaluated retatrutide against placebo and an active comparator, reporting clinically meaningful reductions in HbA1c together with weight loss across the dose range
Science 359 , 11611166 (2018)
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