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Alternative medications include: TNF agents such etanercept (Enbrel), infliximab (Remicaide), or adalimumab (Humira) IL-17 agents such as secukinumab (Cosentyx) and ixekizumab (Taltz) Tofacitinib (Xeljanz) a JAK inhibitor (not approved by FDA yet but understudy) These biologic medications may alter the progression of disease by treating inflammation and preventing the development of fibrosis and then bone formation

[PMID: 14778816] PubMed record related to this compound for laboratory literature review

A B12 deficiency injection may be recommended for people who: Have a diagnosed vitamin B12 deficiency Experience ongoing fatigue or weakness Have conditions that affect nutrient absorption Follow diets that may lead to lower B12 intake Healthcare professionals typically assess symptoms, dietary habits, and medical history before recommending hydroxocobalamin injection

Frontiers in Pharmacology