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Sarilumab has been widely applied in RA treatment, demonstrating significant benefits in improving joint mobility (as measured by ACR20, ACR50, and ACR70 response rates, indicating 20%, 50%, and 70% improvements, respectively, based on the American College of Rheumatology (ACR) criteria.) and slowing disease progression (as assessed by the modified Sharp/van der Heijde score) (105)

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