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The one signal that deserves genuine attention is the TMAO cardiovascular question a biologically plausible, observationally supported, but contested association rather than a demonstrated harm from supplementation
95% CI, 0.80-0.98)
Rapid weight reductioncommon in the first months of treatment with these medicationsmay not allow sufficient time for physiological adaptation
It is not approved for human or animal consumption and must not be incorporated into food, drugs, supplements, or cosmetics
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