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However, the appearance or disappearance of any melanocytic lesion should be brought to the attention of a physician

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The analysis of lipid metabolism in case of concomitant administration of HFD, L-carnitine and EPA compared to that in case of HFD administration demonstrated a significant increase in EPA and DHA levels and a decrease in arachidonate levels (20:4n-6) (Table 4)

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These findings suggest that a mechanism similar to that observed in mice [10] is at work in humans and that combining metformin with DPP-4 inhibitors appears to be a rational way of enhancing GLP-1 signalling in pancreatic beta cells

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