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Liraglutide and semaglutide were predominantly studied in the context of opioid and alcohol use disorders

11.5 Who Should Be Monitored More Closely Monitoring becomes more relevant when: Weight loss exceeds 1520% Appetite suppression leads to persistent under-eating GI symptoms persist Pre-existing marginal status exists Combination therapy (e.g., metformin) is used Older adults are treated Oversight should be proportional to risk

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Norwitz says.The most common electrolyte-related issues stem from two primary mechanisms:Gastrointestinal losses (from vomiting or diarrhea)Reduced dietary intake (from appetite suppression)Here's what can happen and what matters:Metabolic alkalosis (persistent or severe vomiting)"Repeated vomiting can lead to a loss of chloride and potassium, often with metabolic alkalosis (an increase in blood pH) and altered sodium levels," Dr