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Interestingly, patients receiving tirzepatide report reduced overall GI AEs (40%), nausea (17.4%), diarrhea (13.2%) and vomiting (5.7%) compared to patients on semaglutide (43%, 19.2%, 13.7%, and 8.1% respectively)
When a company loses its clinical advantage in a market that propelled its premium, the re-rating process rarely concludes in just one day
These findings suggest that it is possible to increase GLP-1 secretion and manage T2DM and its complications by restoring and improving the gut microbiota [158]
Thats why Affinity patients often combine GLP-1s with hormone optimization and nutrition support
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