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We also sought to establish the impact of the C-terminus on signal bias resulting from modifications elsewhere in the molecule

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Wilding JP, Batterham RL, Calanna S, et al

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In STZ-induced diabetic mice, proximal tubule specific knockout of phosphofurin acidic cluster sorting protein 2 (PACS-2) gene severely impaired reticulophagy of tubular cells and aggravates kidney injury

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Both SUSTAIN-6 and LEADER showed a statistically significant decrease in MACE [53, 54]

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