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typically resolving within 1-2 days of implant placement Expected effects : Skin hyperpigmentation at implant site and systemically (expected pharmacological effect) Melanocytic monitoring : Low rates of new nevi (4% versus 2% placebo in Phase 3)

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these agents should be used with caution in patients with existing cardiac conditions [15] [16] Bullous pemphigoid : A rare skin blistering condition has been reported with long-term use of some gliptins, as noted in MHRA safety communications