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In one 2024 study, researchers found people with type 2 diabetes taking semaglutide were about four times more likely to develop NAION than people with similar health conditions not on the drug
These include: Pancreatitis Increased heart rate An increased risk of gallbladder disease Low blood sugar (hypoglycemia) Kidney problems Increased risk of thyroid cancer or tumors Allergic reactions like skin rash, swelling, breathing difficulties Talk to your healthcare provider right away if you experience any side effects while taking oral semaglutide or semaglutide injections
Following a subcutaneous injection of PT-141, maximal levels occur after about one hour, with a range of 30 minutes to one hour [6]
Major trials including STEP 1-4 (semaglutide) and SURMOUNT 1-4 (tirzepatide) demonstrate 15-22% average weight loss over 68 weeks with improved cardiovascular markers and glucose control
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