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This is harder on GLP-1s because your appetite is suppressedyou need to prioritize protein even when you don't feel like eating
Tirzepatide targets both the GIP (Glucose-dependent insulinotropic polypeptide) and GLP-1 receptors, enhancing insulin secretion and reduces glucagon secretion in a glucose-dependent manner, contributing to improved glycemic control
Important Context for Comparisons Researchers caution against direct comparisons because the data comes from different trial contexts: Trial phase: Retatrutide data is primarily from Phase 2 trials
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