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PIONEER 4 PIONEER 4 was an important trial comparing the addition of oral semaglutide or liraglutide to background metformin with or without an SGLT-2 inhibitor in patients with T2DM
Its only been a month and I already lost 8 lb the staff and the doctor are super nice
Key Takeaways: Patients lose 1 to 3 pounds each week with medical guidance
If tirzepatide causes you to become dehydrated, and you are already on bupropion which has lowered your seizure threshold, the combined situation could increase seizure risk beyond what either medication would cause independently
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